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Aktif
Ofis
Boston, Massachusetts
Yayınlandı · 20.09.2026
Greenhouse (US)

# Associate Director, Clinical Supply Chain

Olema Oncology

Olema Oncology is&nbsp;a clinical-stage biopharmaceutical company committed to transforming the standard of care and improving outcomes for patients living with&nbsp;breast cancer&nbsp;and beyond.&nbsp;It’s&nbsp;an exciting time to be part of Team Olema,&nbsp;with&nbsp;our transformation into a fully&nbsp;integrated oncology company well underway,&nbsp;top-line data from our lead program expected&nbsp;later&nbsp;this&nbsp;year,&nbsp;and our first potential commercial launch on the horizon. Our lead&nbsp;product candidate,&nbsp;palazestrant, is&nbsp;a novel, orally&nbsp;available&nbsp;complete estrogen receptor antagonist (CERAN)&nbsp;and selective estrogen receptor degrader (SERD)&nbsp;currently in&nbsp;two&nbsp;pivotal&nbsp;Phase 3&nbsp;clinical&nbsp;trials.&nbsp;We expect top-line data from OPERA-01,&nbsp;our&nbsp;ongoing&nbsp;Phase 3 trial of&nbsp;palazestrant&nbsp;as a monotherapy in patients with&nbsp;second- or third-line&nbsp;ER+/HER2-&nbsp;metastatic breast cancer (MBC), in the fall&nbsp;which, if successful, could lead to our first potential&nbsp;approval and&nbsp;commercial launch&nbsp;in 2027. OPERA-02,&nbsp;our&nbsp;Phase 3 trial of&nbsp;palazestrant&nbsp;in combination with&nbsp;ribociblib&nbsp;in patients with frontline&nbsp;ER+/HER2- MBC, is&nbsp;enrolling patients.&nbsp;Together&nbsp;with its&nbsp;mechanism of action, pharmacokinetic properties,&nbsp;and&nbsp;the potential to&nbsp;demonstrate&nbsp;activity in both&nbsp;ESR1&nbsp;wild-type and mutant tumors,&nbsp;palazestrant&nbsp;has the potential to&nbsp;transform the metastatic breast cancer treatment paradigm and&nbsp;access&nbsp;a&nbsp;$15 billion&nbsp;global market opportunity. Our follow-on product candidate, OP-3136, is a potent KAT6 inhibitor with&nbsp;the&nbsp;potential to generate further value and meaningfully&nbsp;impact&nbsp;the&nbsp;metastatic breast&nbsp;cancer&nbsp;treatment landscape – particularly in combination with&nbsp;palazestrant.&nbsp;We recently reported&nbsp;encouraging&nbsp;Phase 1&nbsp;monotherapy&nbsp;data from this program&nbsp;across multiple solid tumor types and&nbsp;are&nbsp;advancing&nbsp;patient&nbsp;enrollment in the&nbsp;ongoing&nbsp;combination&nbsp;arms&nbsp;in MBC. Aspiring to transform the metastatic treatment paradigm&nbsp;is an ambitious endeavor that requires a&nbsp;resolute approach to&nbsp;developing better therapies and a&nbsp;passionate&nbsp;team&nbsp;dedicated to&nbsp;helping the patients we serve feel&nbsp;better,&nbsp;longer.&nbsp;We&nbsp;possess&nbsp;a&nbsp;deep&nbsp;commitment to&nbsp;our shared purpose,&nbsp;the&nbsp;sustained pursuit of excellence, cultivating&nbsp;the&nbsp;courage&nbsp;required&nbsp;to advance our programs, drive to succeed, and a collective capacity for adaptability through learning, growth, and evolution.&nbsp; Team Olema is made up of nimble self-starters who bring consistency in their quest for the extraordinary every single day. If&nbsp;you’re&nbsp;ready&nbsp;to be&nbsp;part of a&nbsp;tenacious,&nbsp;courageous,&nbsp;agile, and&nbsp;growing&nbsp;team,&nbsp;join us in making&nbsp;a profound impact,&nbsp;together&nbsp;–&nbsp;for our patients, for your career,&nbsp;and&nbsp;for&nbsp;what’s&nbsp;beyond.About the Role &gt;&gt;&gt;&nbsp; Associate Director, Clinical Supply Chain&nbsp; As the Associate Director of Clinical Supply Chain reporting to the Vice President, Clinical Supply Chain, you will plan, create, implement, build, and optimize the clinical supply chain to ensure uninterrupted and timely clinical drug supply for Olema’s clinical programs.&nbsp;&nbsp;&nbsp;&nbsp; This role is available in either our San Francisco or Cambridge office and will require about 15% domestic or international travel. Your work will&nbsp;primarily&nbsp;encompass:&nbsp;&nbsp; End to End clinical supply chain management&nbsp;&nbsp;&nbsp; Develop and implement global Clinical Supply Chain strategies&nbsp;&nbsp; Manage global inventories, shipping, and third-party manufacturers /&nbsp;logistics&nbsp;providers&nbsp;&nbsp; Develop and manage Interactive Response Technologies (IRT) systems&nbsp;&nbsp; Oversight packaging, labeling, and distribution activities at multiple vendors&nbsp;&nbsp; Generate and manage clinical labels&nbsp;&nbsp; Identify&nbsp;supply chain risks, escalate if needed, and close out risk items&nbsp;&nbsp; Partner with Clinical Operations to align on assumptions and build clinical supply to meet program demand&nbsp;&nbsp; Represent Clinical Supply Chain on study execution teams&nbsp; Knowledge:&nbsp;&nbsp; Bachelor's degree is&nbsp;required,&nbsp;Master’s&nbsp;degree is preferred&nbsp;&nbsp;&nbsp; Late phase clinical development and clinical supply chain management&nbsp;&nbsp; Thorough knowledge of Good Manufacturing Practices (GMP)&nbsp;&nbsp; Experience:&nbsp;&nbsp; 8+ years of biotechnology/pharmaceutical industry experience&nbsp;in clinical supply chain management&nbsp;&nbsp; Inventory management and third-party&nbsp;logistics&nbsp;oversight experience&nbsp;&nbsp; Extensive experience managing forecast demands&nbsp;&nbsp; Prior experience managing global, large, late-stage studies with standard of care drugs&nbsp;&nbsp; Strong global shipping and customs experience&nbsp;&nbsp; Solid experience developing clinical labels&nbsp;&nbsp; Experience developing IRT specifications&nbsp;&nbsp; Hands-on experience and troubleshooting&nbsp;proficiency&nbsp;with QMS and&nbsp;purchasing&nbsp;systems&nbsp;&nbsp; Prior experience in oncology trials using small molecules is preferred&nbsp;&nbsp;&nbsp; Excellent project management skills&nbsp;&nbsp; Attributes:&nbsp;&nbsp; Excellent verbal and written communication and skills&nbsp;&nbsp; Analytical thinking with problem-solving skills and the ability to adapt to changing priorities and deadlines&nbsp;&nbsp; A commitment to excellence&nbsp;&nbsp; Self-motivated and enthusiastic; fast learner who can identify the core project challenges and expeditiously change course as&nbsp;required&nbsp;in a fast-paced organization&nbsp;&nbsp; Teamwork and collaboration; balances team and individual responsibilities; gives and welcomes feedback; puts success of team above own interests; supports everyone's efforts to succeed; shares&nbsp;expertise&nbsp;with others&nbsp;&nbsp; Entrepreneurial mindset and the ability to prioritize key work streams and requirements that will change over the near and mid-term&nbsp;&nbsp; A demonstrated ability to make decisions on incomplete information and in areas where a high degree of professional judgment is&nbsp;required&nbsp;&nbsp; Be a “difference maker” in terms of one’s professionalism and contributions&nbsp;&nbsp; Have impeccable professional ethics,&nbsp;integrity&nbsp;and judgment&nbsp;&nbsp; Be collegial, hard-working, confident, a self-starter and have a passion for results&nbsp; The base pay range for this position is expected to be $185,000 - $200,000&nbsp;annually,&nbsp;however&nbsp;the base pay offered may vary depending on location, market, job related knowledge, skills and capabilities, and experience. The total compensation package for this position also includes equity, bonus, and benefits.&nbsp; #LI-CK1Important Information &gt;&gt;&gt; We provide equal opportunity to all employees and applicants for employment and believe that great ideas and discoveries come from a mix of expertise, background, and experience. Olema is building a culture where the value of difference is celebrated. We offer a competitive compensation and benefits package, seeking to provide an open, flexible, and friendly work environment to empower employees and provide them with a platform to develop their long-term careers. A Summary of Benefits is available for all applicants. Please note: Olema doesn’t accept agency resumes and is not responsible for any fees related to unsolicited resumes. Thank you. Fraud Alert: &nbsp;We are aware of employment scams where individuals pose as representatives of Olema Oncology&nbsp;and make false use of our company name to defraud job seekers. To protect yourself, please note that Olema’s official email addresses end in @olema.com. Our official corporate website is&nbsp;olema.com; our careers page is&nbsp;olema.com/careers; our LinkedIn page is&nbsp;linkedin.com/company/olema-oncology.&nbsp;Please visit these links for official information from Olema. Communication from any other variant is fraudulent. Olema does not conduct interviews via text message/messaging platforms, will not ask you to download anything as part of your interview, will never request any form of payment, provide upfront payments&nbsp;of any kind, and does not make job offers without an in-person interview.

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